Spravato ® (Esketamine) Treatment
Spravato, a derivative of esketamine, creates a transformative journey for the mind. As a breakthrough medicine, it can rapidly reduce the symptoms of anxiety and depression, offering new possibilities for mental well-being.


What is esketamine?
Esketamine is clinically proven to reduce the symptoms of treatment-resistant depression. Derived from ketamine, a well-known anesthetic, esketamine is administered as a nasal spray and acts quickly, providing rapid relief for anxiety and depression.
The Science:
Rapid Relief
Esketamine immediately impacts brain cells, providing relief from symptoms of depression within hours. Esketamine is especially effective at reducing suicidal thoughts.
Cell Communication
Esketamine increases levels of glutamate and dopamine, two key chemical messengers, within the brain. Increased signaling improves brain cell communication, creating a more dynamic network.
Form New Connections
Esketamine helps repair neurons damaged by chronic depression, restoring and enhancing new neuron connections.
Spravato: Frequently Asked Questions
What is Spravato?
Spravato is the brand name for esketamine. It’s derived from ketamine, a well-known anesthetic, and is administered as a nasal spray that acts quickly, providing rapid relief for anxiety and depression.
Am I a good candidate for Spravato?
Determining whether you’re a suitable candidate for Spravato involves a thorough evaluation by a Headlight clinician. Spravato is prescribed for individuals with treatment-resistant depression or Major Depressive Disorder that hasn’t responded to other treatments. Factors such as medical history, current medications, and overall health will be considered.
What should I expect while using Spravato?
Spravato is administered as a nasal spray at select Headlight offices. After administration, you may experience dissociation, dizziness, or sedation, so it’s important to have someone available to drive you home. Your clinician will provide guidance and monitor your response during and after each session. It’s important to discuss any concerns or questions with your provider for a personalized understanding of what to expect during your Spravato treatment.
Are there side effects?
Common side effects may include dissociation, dizziness, nausea, and increased blood pressure. It’s crucial to discuss potential side effects and your medical history with your clinician for personalized information and guidance.
Is Spravato FDA approved?
Yes, Spravato is approved by the U.S. Food and Drug Administration (FDA) for the treatment of treatment-resistant depression and Major Depressive Disorder.

More than 50% of Americans struggle with mental health.
Headlight is now collaborating with health plans and companies to make therapy more accessible and affordable. Get scheduled now.







